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(81) Evidence-based care at your fingertips: The Adapted Resource and Implementation Application (ARIA) Guide interactive portal for comprehensive childhood cancer management

Location: Exhibit Hall D
Title: Evidence-based care at your fingertips: The Adapted Resource and Implementation Application (ARIA) Guide interactive portal for comprehensive childhood cancer management

Abstract : Basis of inquiry: Pediatric hematology/oncology nurses are critical in recognizing and managing toxicities from cancer and blood disorders and their treatment. Barriers such as limited access to clinical guidelines, insufficient knowledge, and workload constraints hinder evidence-based practice at the bedside.

Purpose/objectives: The ARIA Guide is a free, web-based clinical tool designed to provide resource-adapted, evidence-based clinical practice recommendations (CPRs) and tools to healthcare professionals. It aims to provide user-friendly access to the best available evidence for managing childhood cancer, treatment-related toxicities, and comorbidities.

Methods: CPRs for supportive, palliative, and survivorship care are developed through a systematic search for guidelines, quality appraisal, recommendation synthesis, and expert review, including nursing representatives. Contextual adaptations address resource-related barriers using a panel of experts from variously resourced settings. Recommendations are presented in an accessible, interactive format. Additional bedside tools, including antimicrobial dosing and risk assessment tools, were developed in collaboration with global experts using user-centered design methodology. The interface is refined iteratively based on formal usability testing and informal feedback via the ‘contact us’ button. Usability testing used a think-aloud protocol to test 5 heuristic tasks on the web portal. Testing was completed with 20 multidisciplinary clinicians, including nurses, from 17 countries in December 2024.

Outcomes: Currently, 20 CPRs are available, with 75 in development, covering oncologic emergencies, infection- and treatment-related complications, and palliative and end-of-life care. Interactive tools support clinical decision-making, such as determining body surface area, neutrophil count, chemotherapy-induced nausea/vomiting risk. Early user feedback indicated users found the web portal intuitive, easy to use, and contained important content that could support their work. Areas identified to improve usability included enhanced search functionality, quick links, algorithms, figures, and PDF exports. An easy-to-use web portal increases accessibility to practical guidance for nurses caring for children with cancer and hematological disorders in a variety of settings.